Isaac married Eliza Buchanan Wade in 1839 in Omemee, Ontario, Canada. Eliza was born in 1816 in Cavan, Republic of Ireland; died on 1 Feb 1898 in Welcome, Ontario, Canada; was buried in Riverside Cemetery, Lindsay, Ontario, Canada. [Group Sheet] [Family Chart]

1. Theresa Rea was born on 7 Jan 1848 in Victoria County, Ontario, Canada; died on 3 Jan 1924 in Lindsay, Ontario, Canada; was buried on 5 Jan 1924 in Riverside Cemetery, Lindsay, Ontario, Canada.
2. Dr. Henry T. Rea was born in 1855 in Reaboro, Ontario, Canada; died on 30 Mar 1923 in London, Ontario, Canada; was buried in Riverside Cemetery, Lindsay, Ontario, Canada.